The Wen lab at the University of Nevada, Reno studies inflammation in health and disease. We aim to understand how the immune system functions, involving especially neutrophils in inflammation. The primary focus is to apply biosensors and transgenic mouse models to directly visualize immune cell recruitment and function during inflammation, infection and tissue injury in vitro and in vivo. We study inflammatory responses and signaling at molecular, cellular and whole organism levels using state-of-the-art technology, including genome editing, multicolor flow cytometry, TIRF microscopy, intravital imaging, resonant-scanning confocal, and FRET microscopy.

Recent News & Achievements

• Congratulations to Serena Lee! Serena has been selected as a recipient of a travel award from the Microcirculatory Society and will present at Vascular Biology 2024 (October 20 -24) at the Asilomar Conference Grounds in Monterey, California.  

• An abstract coauthored by Serena Lee and Gulinare Halimu has been accepted for presentation as a short talk at the Vascular Biology 2024 meeting. Way to go!

• 8/26/24 Paula Cedeno Guzman joined our lab for a lab rotation as a PhD student. Welcome!

• 8/23/24 Serena Lee received the Best Oral Presentation Award at the 2024 Bierkamper Symposium at the University of Nevada, Reno main campus. Congratulations!

• We are now funded by an R01 grant from the NIH to study molecular mechanisms of neutrophil adhesion in inflammation.